Clinical Evidence | Nalu Medical
Our Evidence is Unprecedented
At Nalu, we’re setting a new standard for pain outcomes.
Nalu’s technology consistently delivers “ 80-50-70” results, regardless of the nerve treated.
80%+
of patients using Nalu
50%+
achieve 50% or more pain relief by study end
70%+
average pain reduction of Nalu Patients
We work tirelessly to help patients who are suffering from chronic intractable pain and our evidence shows proven and predictable results.
Repeated 80-50-70 results in Nalu clinical studies
Consistent real-world outcomes confirming clinical study results
Improved economics for payers, patients, and society
Durable outcomes created by Nalu's advanced technology
Clinical Trials
Repeated 80-50-70 results in Nalu clinical studies
92%
Are very satisfied or satisfied with the system (12 months)
COMFORT (1 Year)
A landmark clinical study for PNS
Nalu PNS was highly effective versus control regardless of treated target
87% responder rate (≥50% pain relief) with 69% average pain relief
View Clinical Evidence Resources
Real-World Evidence
Consistent real-world outcomes confirming clinical study results
4M+
Real-world data captures variability that may be missed inside a controlled setting and provides an additional perspective into patient and provider impact. With over 4M+ patient days since launch, we have a significant and growing data set.
94%
Providers: 94% agreed that successful permanent PNS may reduce opioid use
Real World Evidence from 2,300+ Patients
33 different nerves and 34 nerve combinations treated
94% responder rate for MCID (PGIC)
Health Economic Data
Improved economics for payers, patients, and society
50%
Reduction in total medical costs (1 yr pre vs 1 yr post implant)
All information is based on actual claims data as opposed to a model.
31% reduction in number of patients using opioids
22% reduction in pharmacy costs
Change in Healthcare resource utilization and costs 12 months before and 12 months after Nalu PNS implant
Following PNS implantation, healthcare costs and opioid use were reduced compared to conventional treatment alone
61% reduction in outpatient costs
16% reduction in outpatient doctor visits
View Health Economic Resources
Technology
Durable outcomes created by Nalu's advanced technology
Nalu pulse stimulation pattern waveform
Proprietary waveform designed to invoke multiple mechanisms of action from a single waveform
Scheduling
The ability to cycle through up to four multi-area programs automatically in sequence or random order
Multi-electrodes
Multiple electrodes can be used to deliver electrical impulses to a targeted area
Multi-area
Tonic stimulation pattern sequentially delivered in two to four areas
Current steering
Direct electrical currents through specific electrodes to create a focused electric field in targeted areas
Upgradable system
The micro-IPG software can be upgraded as new capabilities are cleared for use
The Nalu micro-IPG has more complex programming capabilities than other PNS system
Nalu continues to explore new and better ways to understand optimal treatment to improve patient care.
Our latest paper explores the optimal stimulation of nerves as we look to enhance patient outcomes.